![]() ![]() They don't even have fangs, and they can't make venom, either. That thing you heard at summer camp about daddy longlegs being the most poisonous creature in the world, but with fangs too weak to bite you? Not true. randimal // iStock via Getty Images Plus Like wolf spiders we met in a previous episode, tiny spiderlings also hitch a ride with mom for a short period of time after hatching.A cellar spider (Pholcus phalangioides). The egg bundle is toted about in their mother’s jaws to reduce the likelihood of being discovered and eaten by tiny predators. After all this drama, the female lays eggs and encases them in a thin cloak of silk. So, to ensure that he will be the proud father of spiderlings, the male removes sperm placed by his betrothed’s last suitor before he makes his deposit. In the spider mating game, it turns out that sperm from the last mating are the ones most likely to fertilize eggs. Female cellar spiders are not necessarily “you and only you” kinds of gals and will often mate with more than one fella. He then deposits the sperm into a cleft in the female’s abdomen where sperm will be stored until the females uses the little wigglers to fertilize her eggs. Male cellar spiders deposit a droplet of sperm onto small web, which is then gathered and stored in an appendage called the pedipalp. Mating is a curious affair in many spiders, including Pholcus. However, the cellar spider can bring down formidable spiders including Australian redbacks, kin to our black widow, and the fearsome huntsman who we will meet in an upcoming episode. I have handled cellar spiders and never been bitten and if this rare event did happen, the spider’s bite is reported to be harmless to humans. In the land down under and some other parts of the world, cellar spiders go by the name of daddy-long-legs, a moniker associated with another arachnid, opilionids, which we met in a previous episode. ![]() Millions of years ago cellars were noticeably absent from the planet, but caves and dank tree hollows were aplenty and cellar spiders found these habitats perfect for building their loose webs for snaring prey. Beneath the web, exsanguinated bodies of small flies, pill bugs, and beetles piled up on the window sill.Ĭellar spiders are found throughout much of the world in temperate and tropical regions. Just on the other side of the glass, the cellar spider employs the same strategy for trapping small insects drawn to the light of a window in a futile attempt to escape the confines of a basement. ![]() In last week’s episode, we met the common house spider that exploits outdoor window frames to string her web and capture prey. Near the corner of one dimly lit window, I discovered a diverse collection of tiny insect carcasses and didn’t have to look far to see a gangly and beautiful cellar spider hiding in the upper corner of the window. Part of the assignment was to inspect windows and remove any arthropods living or dead that might terrorize visitors who do not share affection for animals lacking fur and possessing more than four legs. With the holiday season fast approaching and family and friends soon to visit, the Bug Guy received orders to prepare the spare bedroom in the basement for overnight guests.
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4/18/2024 0 Comments Beersmith 3 wine ingredientsI rarely miss my targets and when I do can trace it back to something I didn't follow, maintain, or do correctly (oops, forgot to adjust the mill back after grinding oat malt). I've been using it for 5 years now and would not be without it. ![]() Weak areas: Water profile tool is new and a bit clumsy, whirlpool hop additions don't account for temperature drops, volume adjustment for temperature is really non-existent (either hot or not), inventory control, brew timer does not allow for delay activities (end of boil vs whirlpool addition). Strong points: Recipe formulation, water volume calculations, gravity predictions, all-in-one with multiple tools for gravity adjustment, refractometer and hydrometer adjustments, etc., most of the calculations are user adjustable for your system, brew log function is great for archiving finished recipes and separating them from recipe library. Sometimes they start off pretty crude in operation and take several updates to iron out the weak points (like, for instance, the water profile tool and pH predictions). Brad does try to keep up with some of the latest developments in brewing and apply them to the software. The interface is OK, not real intuitive, but workable. It does take some time to 'tune' to get good results in predicting what your process will produce. If you like designing your own recipes or modifying recipes you find on-line, then it is well worth the relatively low price. If you buy and brew pre-made kits, then it is probably an OK investment, but it is not going to be of greatest value. It is a neat platform for any crafting enthusiasts out there who wants to test their skills in creating the best drink possible.It really depends upon how your brew. All things consideredīeersmith is a smart application for crafting new beer recipes and other beverages. Download BeerSmith 3 beer brewing, mead, wine, and cider recipe software here BeerSmith includes beer recipe design, management and a complete set of brewing tools for the homebrewer or professional brewer. Of course, when it comes to crafting, a bit of experimentation is in order before achieving a masterpiece, and that's what this program is about. The amount of details that go into creating the perfect batch seems overwhelming. On the other side, if you have a history in brewing, and on top of that,have been dealing with similar applications, Beersmith will fit you like a glove. all elements that must require a bit of know-how from the user's behalf. Types, batch size, boil time, ingredients, tools, temperatures, carbonation, fermentation, etc. For the untrained eye, once a recipe is opened, a stream of data will burst out. If you are a beginner who tries to get into crafting beer with zero information on board, Beersmith will hit you like a truck. All the information you need is packed into this app ![]() So yes, you can craft other types of drinks if you get beer burnout. What stands out from that neat beverage list are words like mead, cider, and wine. Beersmith comes with a dozen of recipes in order to showcase its layout and mode of operation. With a name like that, beer must be sounding like an exclusive item. Take Beersmith for example, a professional application that not only holds the recipes for you, but it shows you how to execute them and most importantly, allows you to try new combinations. Nowadays, recipes of all kinds are no longer paper-dependable, so you can store all your secret information inside purposely developed applications. ![]() Drinking beer is one thing, everybody can do it, but crafting your own recipe or brewing successful beverages must be feeling more accomplishing. 4/18/2024 0 Comments Moca cognitive assessment norms![]() Working Memory/Attention/Executive Control This scale consists of Clock Drawing and the Benson Figure Copy. Recognition of whether words appeared in the CERAD list and which one of four complex figures was copied are assessed. The CERAD 10-Word list is presented over three trials.ĭelayed recall of the CERAD Word List and the Benson Figure Copy are assessed after at least 10 min. There are 12 items included: year, month, day, date, season, place/building, floor, city, province, country, Prime Minister, and Premier of the province. The advantages of an electronic application include automatic scoring, automatic point-of-care data collection for potential data entry into a clinical or research registry, a printable summary of results, and graphical representation of percentile performance on each cognitive domain. In addition to the paper version, we developed an electronic application for the iPad and assessed equivalency between the two versions. Our objectives were to obtain normative data on the TorCA and to validate this test for detection of amnestic mild cognitive impairment (aMCI). This was done through the addition of more robust verbal learning and delayed recall, a complex figure copy with delayed recall, semantic knowledge items, a version of Trails A and B, and revision of the subset of language tests. To accomplish this goal, the psychometric properties of the Behavioural Neurology Assessment, a screening test covering a broad spectrum of cognitive functions for diagnosing mild to moderate dementia, were significantly enhanced to detect mild cognitive deficits by development of the Toronto Cognitive Assessment (TorCA). Consequently, given the growing emphasis on early detection of cognitive impairment, there is a need for assessment tools that are intermediate between brief screening tests and neuropsychological batteries, can be administered by physicians as well as any health care professional or trained assistant in any medical setting, and can accurately identify mild cognitive decline. Neuropsychological assessments facilitate better understanding of cognitive performance for diagnosis but are time consuming, resource intensive, and suited for administration only by neuropsychologists-a resource that is often not readily available. ![]() Future studies will focus on cross-validating the TorCA for aMCI, and validation for disorders other than aMCI.īrief tests such as the Mini-Mental State Examination (MMSE) and the Montreal Cognitive Assessment (MoCA) are popular screens for cognitive function. The TorCA can improve resource utilization by identifying patients with aMCI who may not require more resource-intensive neuropsychological assessment. Paper and iPad version scores were equivalent. In an exploratory logistic regression analysis, indices of Immediate Verbal Recall, Delayed Verbal and Visual Recall, Visuospatial Function, and Working Memory/Attention/Executive Control, a subset of the domains assessed by the TorCA, correctly classified 92% of participants (sensitivity 92% specificity 91%). The total score correctly classified 79% of participants (sensitivity 80% specificity 79%). The TorCA provides a stable assessment of multiple cognitive domains. Cognitively normal participants were recruited from both healthy volunteers in the normative study sample and the community. For the validation study, the sample was comprised of participants with aMCI or normal cognition based on neuropsychological assessment. For the normative study, healthy volunteers were recruited from the Rotman Research Institute registry. We obtained normative data on the TorCA ( n = 303), determined test reliability, developed an iPad version, and validated the TorCA against neuropsychological assessment for detecting amnestic mild cognitive impairment (aMCI) ( n = 50/57, aMCI/normal cognition). ![]() The Toronto Cognitive Assessment (TorCA) was developed to achieve these goals. Black 1, 4, 9, 17, 20, 25 na1 &Īlzheimer's Research & Therapy volume 10, Article number: 65 ( 2018)Ī need exists for easily administered assessment tools to detect mild cognitive changes that are more comprehensive than screening tests but shorter than a neuropsychological battery and that can be administered by physicians, as well as any health care professional or trained assistant in any medical setting. The Toronto Cognitive Assessment (TorCA): normative data and validation to detect amnestic mild cognitive impairment ![]() These highlands have a cooler climate than the rest of the country, and the rich soil supports the cultivation of tea and coffee, two of Kenya's main export crops. Among these are Mount Kenya, the country's highest point at 5,199 m (17,057 ft) above sea level, and Mount Elgon, which borders Uganda. The Western Highlands: To the west of the Rift Valley rise the Western Highlands, which include several of the highest peaks in Africa. Towns such as Nakuru and Naivasha dot the valley, and it's also home to renowned natural parks like Hell’s Gate and Lake Nakuru National Park. The Valley hosts a significant portion of the country's population due to its fertile volcanic soils suitable for agriculture. The Rift Valley bisects Kenya from north to south, featuring a chain of volcanoes, some of which are still active, and several freshwater and alkaline lakes. It supports grassland vegetation and is mainly used for ranching and farming, although it is also part of the ASALs and is considered semi-arid. The plateau's altitude varies between 300 m (984 ft) and 900 m (2,953 ft) above sea level, but the Chyulu Range and the Taita Hills reach over 2,134 meters (7,000 feet). This expansive region consists of a series of low-lying plateaus and plains, interspersed with minor hill ranges and inselbergs. The Eastern Plateau: Inland from the coast, the land rises into the Eastern Plateau. Mombasa, the major city in this region, serves as an important commercial and tourism hub. The coastal region has a warm, tropical climate which supports the growth of mangrove swamps, palm trees, and the proliferation of various agricultural crops like coconuts, cashews, and citrus fruits. This area features a low-lying, fertile plain with several river deltas. The Coast: Kenya's coastal area along the Indian Ocean extends roughly 536 km (333 mi). The country's geography divides roughly into the coastal areas, the Eastern Plateau, the Rift Valley, the Western Highlands, and the Northern Desert, which is part of the Arid and Semi-Arid Lands (ASALs) of Kenya. The total area of Kenya encompasses approximately 580,650 km 2 (224,962 mi 2). Its southeast flank abuts the Indian Ocean. Kenya, an east African country, shares borders with five other countries: Uganda to the west, South Sudan to the northwest, Ethiopia to the north, Somalia to the east, and Tanzania to the south. 4/17/2024 0 Comments 2048 x 1152 bmw banner![]() Under the "Banner image" tab, you'll see two options- "Change" and "Remove". Click on the camera icon on the top right of your channel banner to open your YouTube studio.Ĥ. Once you've clicked on "Your channel", you’ll land on your YouTube channel.ģ. Select your profile picture and select the "Your channel" tab.Ģ. How to change YouTube banner on computer:ġ. For the best results, the recommended channel art size is 2560 x 1440 pixels with an aspect ratio of 16:9, and the max file size is 6MB.įotor's YouTube banner templates are designed with YouTube banner image guidelines in mind so that you never have to worry about whether your banner will get cropped or stretched when uploading to YouTube. Your YouTube banner looks different across different sorts of devices- mobile, desktop and TV screens. YouTube Banner Design FAQs How Big Is a YouTube Banner? Once you're happy with your YouTube banner design, download it with your desired format and you're ready to go. There are unlimited ways to personalize your YouTube banner.ĥ. Explore millions of backgrounds, illustrations, vectors, icons, stock photos, and more. You'll find all the design elements you need to create banner images for YouTube. ![]() To help people quickly understand what type of videos you're creating, you can add a short description about your channel, a tagline, and even your posting schedule on the banner.Ĥ. Customize the text, colors, font styles, and photos with drag-and-drop editing tools. Click on the template that you like to start designing.ģ. Browse through the template library or use the search bar to find a specific type of YouTube channel art templates you want. Open in your web browser, then choose the "YouTube Channel Art" template layout.Ģ. With Fotor's online YouTube banner maker, you can design and create YouTube banner designs like a pro, even if you’re a design newbie.ġ. No design experience or skills are required. Beyond that, YouTube banner templates are 100% customizable, and our powerful YouTube banner maker makes it simple for you to edit the template to suits your specific needs. ![]() No matter what your channel is about- sports, comedy, fashion, beauty, gaming, food, or lifestyle focus, you’ll easily find the right fit for your channel. To help you create a pro-looking YouTube banner easily and quickly, we provide you with a huge library of professionally designed YouTube banner templates in various themes and styles. For this reason, having a custom YouTube banner that makes a good first impression is strongly recommended. A YouTube banner is a cover photo or header image that appears on the top of your YouTube channel, the most prominent thing first-time viewers see when they visit your channel. Just begin your journey on YouTube? Be sure to make an attention-grabbing banner image for your YouTube channel. Customizable YouTube Banner Templates for Every Type of Channel ![]() Install instructions are included with each download but you can also download instructions here: ![]() If you have any issues with the checkout process please feel free to Contact Me with your registered User Name. You will find all your purchased downloads on the My Downloads page You will then have access to the Cart to add multiple purchases in a single transaction. Please Login or Create an Accountto purchase and download the files. You also need the below "Hardware Library" expansion update for all the latest content since Omnisphere 2.4 such as the 1600 preset Hardware Library content. You can download and install this for free to test things out before purchasing the full NKS browser pack.įull Version For Omnisphere 2.4 This is the full library for Omnisphere content up to v2.4. The Free Download Version contains a handful of presets to test how the NKS installation and compatibility will work. VST2 versions are still available for download in the user downloadarea if required There is only a cost on the factory library, all other expansion libraries, Hardware Library and Sonic Extensions will offer a free update. This library has been updated to work with Omnisphere VST3 so please ensure you have the VST3 version of Omnisphere installed.ĭue to the work involved to update there is a small charge for users who would like to update their previous VST2 library so please login to see your update cost. Supports Maschine Hardware (all versions).Supports Komplete Keyboards (all versions).This is not included with the core Omnisphere download Omnisphere Hardware Library is a separate expansion library of 1600+ presets that you can also add to Omnisphere. Additionally, a Komplete Kontrol database file and plug-in artwork is also included to create entries in your User Library. Sound previews are now also available for your library so you can hear what a preset sounds like before loading the instrument. All presets have been saved as NKS files which contains the Omnisphere preset information, tagging information and mapped controls. This library contains over 7500 factory presets for Omnisphere 2 that can be loaded and browsed directly using the Komplete Kontrol / Maschine software and hardware. The Omnisphere 2 NKS Library is a preset pack for browsing Omnisphere 2 presets from the Komplete Kontrol / Maschine software and hardware. 4/17/2024 0 Comments Command prompt windows 10 listSimilar to the copy con and echo command, which let you create files, Windows also has a similar utility to create folders: it’s called mkdir. When you want to delete all files in a folder: To delete a file from your current directory, run: You can use it in conjunction with switches to get around deletion restrictions on the system. Short for delete, the del command helps you delete files from your computer. You can do this by searching “cmd” in Run and pressing the Ctrl+Shift+Enter keys or by right-clicking on its app icon and selecting Run as administrator. With move, you can move your files/folders by running:ĭo note that you need administrative access on your system to move files/folders around, so make sure you’re running CMD as an administrator before carrying out such operations. Occasionally, however, when you want to relocate a file or directory to a different location and don’t want an extra copy, you need the move command. Using the copy command, you can create a copy of a file on some other location on your computer. Similarly, if there’s a need to combine two files into a new file, enter:Ĭopy file_name_1 + file_name_2 file_name_3 5. When you want to copy a file from a different folder:įor copying multiple files of the same type in a folder to another location: To copy a file from an existing directory, use the following syntax: And, you can even use it to combine multiple files. It comes with a few different switches to help you extend its scope of use and put it to use for your different requirements. Rename C:\Users\Dell\Documents\File1.txt File2.txtĪs its name suggests, the copy command allows copying file(s) from one location on your system to another. If you want to rename the files in other folders, prepend their path before the filename. Run your command in the following syntax to rename a file: The rename command enables you to rename files and folders on your computer right from the command line. Once done, hit Ctrl + Z to save the file.Īlternatively, if you want to create a single-line text file, you can also use the echo command:Įcho your_text_here > file_name_with_extension 3. …and start populating the file with text. Although this is perfectly acceptable, there is another (read efficient) way to accomplish this: it involves running the copy con command in the CMD window to speed up the entire process. If you haven’t used the command prompt much before, you’re probably using Windows’ GUI to create new files. In case you still can’t file your document, you can narrow down your search to a specific set of files:įind /i "command prompt commands" *.txt 2. ![]() To search for text in multiple documents:įind /i "query_string" path\to\file1 path\to\file2 …where /i is a switch to avoid case-sensitive searching.įind /i "command prompt commands" C:\Users\Dell\Documents\Commands.txt So if you’d like to search for a string in a specific file, you’ll need to run: It lets you search for a string in a file or multiple files and returns the lines that contain the text you specified in your query. Findįind is one of the most useful Windows CMD commands. ![]() With that done, all you have to do now to run a command is to type in the command and hit the Enter key. 4/17/2024 0 Comments Cat weight tracker templatingFinally, we evaluate the efficacy of a DDN in inhibiting dengue virus infection via plaque-forming assays. We then present a procedure for synthesizing DDNs using a combination of in silico design principles, self-assembly, and characterization using gel electrophoresis, atomic force microscopy and surface plasmon resonance spectroscopy. We describe how available structural data can be used to identify unique spatial patterns of antigens on the surface of a viral particle. Since these antigens are arranged in a defined geometric pattern that is unique to each virus, the structure of the DDN is designed to mirror the spatial arrangement of antigens on the viral particle, providing very high viral binding avidity. The designer DNA nanostructure (DDN) can bind to complementary epitopes on antigens dispersed across the surface of a viral particle. Here we present the rational design of DNA nanostructures to inhibit dengue virus infection. Central to our ability to successfully tackle these diseases is the need to quickly detect the causative virus and neutralize it efficiently. I have a range of time values, but when I try to sum them, the total is never greater than 24 hours.Emerging viral diseases can substantially threaten national and global public health. I saved my workbook with a password and Excel won't recognize it.
4/17/2024 0 Comments Dorsal column stimulator technique![]() The implanted leads are connected along extension cables that lead to the pulse generator, where the system is programmed by adjusting the amplitude, pulse width, and frequency. The Paddle lead is suitable for patients with a history of lead migration or experiences where the placement of the trial lead was difficult. The placement of the Paddle lead requires open surgery (laminotomy or partial laminectomy), but offers the advantages of greater stability and less propensity to migrate. The Percutaneous electrode can be inserted via Tuohy needles and is ideal for both trial and permanent implants. Currently, there are two types of electrode leads available: the Percutaneous lead and the Paddle lead. Therefore, a lead design which varied in the number of electrodes from four to eight, was subsequently developed. The electrodes that were developed initially were unipolar, and the shortcomings were apparent through its limited field of paresthesia and application. The SCS hardware consists of an electrode lead, an extension cable, a pulse generator, and a programmer. Recently, the outcomes of SCS have improved significantly and have become a widely accepted form of therapy for chronic intractable neuropathic pain. It is strategically aimed to replace the unpleasant sensory experience of pain with a more pleasing tingling sensation referred to as parasthesia. Therefore, the term dorsal column stimulation was replaced with SCS. Low-level electrical impulses, delivered directly into the spinal cord through the SCS that is inserted in the epidural space, interfere with the direct transmission of pain signals traveling along the spinal cord to the brain. However, it has recently been proven that applying an electrical field to the dorsal epidural space might activate a larger number of neural structures. In 1967, Shealy first inserted the dorsal column stimulator into patients suffering from cancer pain. The technique is believed to inhibit chronic pain by stimulating the large diameter afferent nerve fibers in the spinal cord, which is based on the gate control theory of pain proposed by Melzack and Wall. It has been used for approximately four decades in treating chronic neuropathic pains that have been refractory to other conventional treatments. Neuromodulation with Spinal cord stimulation (SCS) is one of the most exciting developments in chronic pain management. All rights reserved.Chronic pain is a leading cause for physical and emotional suffering, familial and social disruptions, disability, and work absenteeism. Published by Oxford University Press on behalf of the American Academy of Pain Medicine. Very low-quality evidence supports dorsal root ganglion neurostimulation for the treatment of chronic pelvic pain, chronic neuropathic groin pain, phantom limb pain, chronic neuropathic pain of the trunk and/or limbs, and diabetic neuropathy.Ĭomplex Regional Pain Dorsal Root Ganglion Stimulation Lower-Extremity Pain Neurostimulation Pelvic Pain. In accordance with the Grades of Recommendation, Assessment, Development, and Evaluation system, low-quality evidence supports dorsal root ganglion neurostimulation as a more effective treatment than traditional neurostimulation for pain and dysfunction associated with complex regional pain syndrome or causalgia. Complication rates vary, though the only randomized controlled trial reported a higher rate of adverse events than that seen with traditional neurostimulation. Significant improvements were also reported in the secondary outcomes assessed, including mood, quality of life, opioid usage, and health care utilization, though a lack of available quantitative data limits further statistical analysis. Cohort data success rates ranged from 43% to 83% at ≤6 months and 27% to 100% at >6 months. 51% of patients who experienced at least 50% relief with spinal cord stimulation at 3 months. A worst-case scenario analysis from the randomized controlled trial reported ≥50% pain relief in 74% of patients with dorsal root ganglion neurostimulation vs. One pragmatic randomized controlled trial, four prospective cohort studies, and eight case series met the inclusion criteria. Secondary outcomes were physical function, mood, quality of life, opioid usage, and complications. The primary outcome was ≥50% pain relief. To evaluate the effectiveness of dorsal root ganglion neurostimulation for the treatment of refractory, focal pain in the pelvis and lower extremities. One benefit compared to Avira’s free-to-use competitor Avast is that while Avast advertises quite intrusively for the paid version in its free version, Avira is much more moderate with its advertising. A 2016 review of Avira Free Antivirus by AV-Comparatives gave the program good grades overall, while a May/June 2022 review of macOS security products awarded high marks to Avira Antivirus Pro. The paid version of the product–Avira Internet Security– received top marks in a September/October evaluation from AV-Test for protection, performance, and usability. But when I tried to open the file, Avira caught and quarantined it. It didn’t scan the eicar.zip file when I downloaded it. The program easily caught and quarantined the different EICAR test files that I tried to download, including the file and the eicar text file. ![]() All you have to do is: Click download to download the installer file. ![]() AVG offers a free virus scanner and malware removal tool which takes seconds to install. To improve your Mac’s performance, Avira Free Security lists a junk cleaner, application uninstaller, and startup manager, but only the junk cleaner is accessible in the free edition.,Īvira was effective at detecting and stopping malware. Its very simple to download and run a free virus scan to check for viruses and other malware on your computer. All of these features pop up in the program’s dashboard, but only a few are actually accessible in the free product.įor alternatives, see our roundup of the best antivirus software for Mac. Free for home use, Avira Free Security starts off with antivirus protection but then lists a VPN, password manager, browser cookie cleaner, junk file cleaner, application uninstaller, startup manager, and PC performance booster. Such is the case with Avira Free Security for Mac. But when you dig deep, you find that most of those extra, advanced options actually require a paid subscription. Some free security programs appear to offer an array of features beyond just basic antivirus protection. But most actually require a paid subscription, so the product’s overall usefulness is limited. The VPN severely limits the amount of encrypted trafficĪvira Free Security for Mac seems to offer a lot of features for free.A smart scan promises to boost your PC’s performance, but there’s little you can do in the free version. ![]() Offers several different tools via its dashboard, but only a few are available in the free version. |
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